Thermal Stability
CombirepelTM has been designed considering the unique requirements of the polymeric and plastics manufacturing industry. Most of these downstream applications require processing additives at elevated temperatures through the process of extrusion. Thus thermal stability is a prime consideration for most additives to be used. CombirepelTM molecules are stable up to 1400oC and thus can withstand almost all polymer processing temperatures.

Extrusion temperatures being as high as 100-300oC, CombirepelTM can be used effectively for processing in polymers while at the same time retaining its efficiency.

Non- toxicity
Most often toxicologists use Lethal Dose and Lethal Concentration to gauge the toxicity of most chemicals; evaluated on many kinds of animals but most often testing is done with rats and mice. The LD50 or LC50 is one way to measure the short-term poisoning potential (acute toxicity) of a material.

It is usually expressed as the amount of chemical administered (e.g., milligrams) per 100 grams (for smaller animals) or per kilogram (for bigger test subjects) of the body weight of the test animal. The LD50 can be found for any route of entry or administration but dermal (applied to the skin) and oral (given by mouth) administration methods are the most common.

Please see the scale on toxicity tabulated by Gosselin, Smith and Hodge.

Gosselin, Smith and Hodge Scale
Probable Oral Lethal Dose (Human)
Toxicity Rating or Class Dose For 70-kg Person (150 lbs)
6 Super Toxic Less than 5 mg/kg 1 grain (a taste - less than 7 drops)
5 Extremely Toxic 5-50 mg/kg 4 ml (between 7 drops and 1 tsp)
4 Very Toxic 50-500 mg/kg 30 ml (between 1 tsp and 1 fl ounce)
3 Moderately Toxic 0.5-5 g/kg 30-600 ml (between 1 fl oz and 1 pint)
2 Slightly Toxic 5-15 g/kg 600-1200 ml (between 1 pint to 1 quart)
1 Practically Non-Toxic Above 15 g/kg More than 1200 ml (more than 1 quart)
     
All grades of CombirepelTM fall under the category 1 i.e. "Practically non toxic".
CombirepelTM has been classified under FIFRA (Section 25 B) as a minimum risk pesticide.